《瓦解新冠病毒：诺贝尔奖成果升级换代产品在纳米水平上化解冠状病毒的另类途径——富勒烯膦酸酯破解冠狀病毒的技术路线》
Disintegrating the New Coronavirus: An Alternative Approach to Disintegrating Coronaviruses at the Nanoscale with Nobel Prize Upgrades
--Fullerene phosphonate technology route to crack coronavirus
（本文在美国科技论文预印本网站发布的英语截图：目录部分）
English screenshot of this article published on the American Scientific Papers preprint website: Section of the directory
中国光彩集团副总裁、
京中智库领袖联盟首席专家、
广顺集团首席科学家 、
国际健康科学院院士
徐群贵研究员
（北京·中国光彩集团）
Vice President of Guangcai Group
Chief Expert of Jingzhong Think Tank Leadership Alliance
Chief Scientist of Guangshun Group
Academician of International Research Institute of Health Science
Researcher Xu Qungui
【内容提要】我们团队针对新冠肺炎病毒COVID-19或者说SARS-CoV-2破解、灭杀的高科技成果，是全球独家的，且完全抛弃了疫苗、抗体的模式，开创了对抗病毒的新纪元。我们从临床医学与纳米化学实验相结合的独特角度，建立了静电粒子剖析病毒结构的完整性理论与实践体系，能够行之有效的破解新型冠状病毒。这是关于生命科学、纳米材料瓦解新型冠状病毒的系统化更新换代，拥有可再生能源中纳米材料的合成、富勒烯聚磷酸二钠物理化学性能和应用于灭杀病毒的实验效果。我们30多年来坚持不懈的精研C60及1996年诺贝尔奖成果的衍生品，我们两年多前成功的制造出来全球唯一油水兼容，且无毒的富勒醇并申请了国际专利。我们的高科技创新成果能够通盘解体各种冠状病毒，不论病株如何突变，都一并瓦解而使得病毒不能危害人类细胞组织，形成的新细胞正常，通过人体器官的新陈代谢排出体外。
Abstract
In mid-May 2020, the Academy of Sciences, the Academy of Medical Sciences, and the Laboratory of the Comprehensive University of Science and Technology (LUSU) have unanimously determined that our team's high-tech achievements in dismantling and killing the Coronavirus COVID-19, or SARS-CoV-2, is not only world's exclusive approach, but by completely abandoning vaccine and antibody approach we have also opened a new era in our battle against viruses. By adopting an unique perspective of combining clinical medicine and nanochemical experiments, we have established a complete theoretical and practical system of electrostatic particle dissection of the viral structural integrity, which can effectively dismantle the Coronavirus. This is a systematic innovation and renovation of the application of life science and nanomaterials in the dismantling of the Coronavirus, which entails the synthesis of nanomaterials in renewable energy, the physicochemical properties of fullerenes disodium polyphosphate, and its application in eliminating viruses. We have been working incessantly on C60 and the derivatives of the 1996 Nobel Prize for more than 30 years, and more than two years ago we were able to produce the world's only oil-water compatible, non-toxic fullerene and applied for a national patent. Our high-tech innovations are able to disintegrate all kinds of coronaviruses, no matter how mutated the strains are, so that the virus cannot harm human cellular tissue, and the new cells that form are normal and excreted through the metabolism of human organs.
【关键词】C60 新冠病毒 静电粒子 疫苗 抗体 病毒结构 富勒烯
聚磷酸二钠 药物副作用
【Keywords】C60 2019-nCoV Electrostatic particle Vaccine Antibody
Structure of the virus Fullerene
Disodium polyphosphate Drug side effects
本文和作者另外两篇文章在美国《科学》期刊科技论文预印本上发布的截图
Screenshots of this article and two other articles published by the authors in a preprint of scientific papers in the American Journal of Science
我们的技术是要在人体和排泄物处理系统灭杀新冠肺炎病毒COVID-19或者说SARS-CoV-2，因为这种病毒已经威胁人类生存。欧洲瑞士日内瓦当地时间2020年5月13日，世卫组织卫生紧急项目负责人迈克尔·瑞安表示，新冠病毒可能成为长期问题，很难预测何时可以战胜病毒，它可能成为永远不会消失的流行性病毒。为此，我们争分夺秒的开展科研工作，我们的實验樣品已经送达(1) 中国哈尔滨，（2）中国武汉，以及其他的五个国家、地区数以百计的医院，集思广益討論實验方案，我们的成果还需要经过嚴格的五千人到一万多人的医学臨床實証。我们的高科技成果能够帮助中国消除全世界起诉、索赔的后果，我们坚信世界各国利用我们的成果可以拯救人类，通过战胜病毒而成功战胜形形色色的病毒，包括武汉2019年底不明肺炎的新型冠状病毒。
Our technique is to kill the neocoronavirus COVID-19 or SARS-CoV-2 inside the human body in the excretory system, for the virus has already threatened the survival of humankind. On May 13, 2020 in local time in Geneva, Europe, Michael Ryan, head of WHO's Health Emergencies Program, stated that the new coronavirus could become a long-term problem, as it is difficult to predict when it can be eradicated, and that it could become an epidemic virus that will never go away. For this reason, we have been working against time, and our samples have been sent to (1) Harbin, China, (2) Wuhan, China, as well as five other countries and hundreds of other hospitals in various regions to discuss the experiment protocols, for our results have yet to be validated by clinical trials with 5,000 to 10,000-plus participants. Our high-tech achievements can help China to eliminate the consequences of worldwide lawsuits and claims, and we are convinced that countries around the world can use our achievements to save humanity by successfully defeating viruses of all kinds, including the new coronavirus of Wuhan pneumonia.
我们乐见其成的同行也是在积极努力，只是没有一个与我们的科技成果在同类型路线图上，最容易被认为是同样的另辟蹊径好消息，是德国法兰克福大学2020年5月14日发表公告，借助一种新型质谱分析技术，科研人员目前已经找到了新冠肺炎一处“弱点”，针对性使用抑制剂可阻止病毒的复制，达到使新冠病毒“绝育”的目的。先天不足的是这种新质谱分析技术在纳米级识别率和可操作性方面还不成熟，研究发现病毒利用细胞的一项合成蛋白机制，复制和分裂其他病毒，只是适应不了病毒变异的蛋白质基因变化。针对这一“弱点”使用抑制剂，去阻止新冠病毒的复制，没有普遍的适应性。当然，和我们同样的认为，病毒失去复制能力后，将会变得非常脆弱，且致病性也会降低。
We are pleased to see that our peers are also actively working, but there is no one with our scientific and technological achievements on the same type of roadmap, the most likely to be considered the same alternative good news, is the announcement of the University of Frankfurt, Germany, on May 14, 2020, with the help of a new mass spectrometry technology, researchers have now found a "weak point" in the new coronary pneum, targeted use of inhibitors can stop the virus replication, to "sterilize" the new coronary virus purpose. The congenital shortcoming is that this new mass spectrometry technique is immature in terms of nanoscale recognition rates and operability, and studies have found that viruses use a synthetic protein mechanism in cells to replicate and divide other viruses, just not to adapt to the genetic changes in the proteins of viral mutations. There is no universal adaptation to the use of inhibitors against this "weakness" to prevent the replication of neocoronavirus. Of course, in the same way that we think that viruses lose their ability to replicate, they become very vulnerable and less pathogenic.
我们是在1996年诺贝尔医学与化学奖成果的“成熟度”基础上向前进，是普遍性的瓦解病毒基因，不是针对病毒的某个弱点。近期的好消息还有中国团队，和美国匹兹堡大学的数个疫苗，已经进入临床试验，再就是牛津大学Jenner Institute团队宣称2020年9月前，新冠疫苗或可批量应用。另外两个国家的两种有效抗体同时面世，只是“抗体”、血清疗法之类的技术副作用、覆盖面都没有“纳米级的瓦解病毒基因”更加安全可靠。现在，新冠病毒“绝育术”的出现，也是缺乏“纳米级的普遍适用能力”。只不过面对新冠病毒，我们必须防治结合两手抓，才能彻底打赢这场人类生命保卫战。因此，无论是抗体，还是疫苗，还是“绝育术”，无论哪一种方法，都值得我们期待。至少这些科技探索发现让全世界深受新冠肺炎荼毒的各国人民，无异于在黑暗中见到了一束又一束曙光。下面，集中力量解读我们的“纳米级瓦解病毒基因”高科技成果。
1、我們將要討論冠狀病毒最外部“触突”那些尖峰糖蛋白，這是一種我們將試圖誘導的，在沒有膜的情況下，發生一種膜融合“接触性纳米级生物反应”。這將是我们的富勒烯聚磷酸二钠进入病毒，通过纳米技术瓦解病毒，保护人体细胞组织和免疫系统的关键性切入点。
We are building on the matured foundation of the achievement of 1996 Nobel Prize in Medicine and Chemistry, a general dismantling of viral genes rather than targeting a specific weakness in the virus. Good news in the recent months also include several vaccines produced by the Chinese team, and by the University of Pittsburgh in the US, are already in clinical trials, and a research team at the Jenner Institute, Oxford University, claims that the new coronavirus vaccine may be available in bulk by September 2020. In two other countries, two effective antibodies are available. However, the technical side effects and the coverage of "antibodies" and serum therapies are not as safe and reliable as the “nano-scaled disintegration of virus genes". Now, the newly emerged Coronavirus “sterilization” also lacks the universal applicability of our nano-scaled approach. Nevertheless, it is paramount that we integrate treatment and prevention in the wake of the coronavirus pandemic to triumph against this present threat to humankind. Whether it is antibodies, vaccines, or viral sterilization, these new achievements certainly worth looking forward to, as they shed rays of hope on the world plagued by the pandemic. In the following paragraphs, we will shift focus to interpreting the high-tech results of our “nano-scale disruption of viral genes".
1. We will discuss the outermost "synapses" of the coronavirus, those spiking glycoproteins, which we will attempt to induce, in the absence of a membrane, a membrane fusion, "contact nanoscale biological reaction". This will be a critical entry point for our fullerene disodium phosphate to enter the virus and disintegrate it through nanotechnology to protect human cellular tissue and the immune system.
为此，我要講的是靜電病毒結構。這是除了磷酸鈉的特性，使富勒烯聚磷酸二钠能夠传递人类免疫系统抗體，以及临床医学其他的抗病毒藥物，实施对于病毒、细菌的结构瓦解“生物反应”。所以，我們不是一站式的疫苗思维方式，也不是药品与病毒打架，或者药品辅助人体免疫系统的路径依赖症。因为，我们知道病理解剖新冠肺炎传染病遗体之后，发现人体免疫系统的细胞因子风暴并没有发作的时候，人体肺部粘膜已经发生了病变。争论病毒是否通过病患者的并发症，或者说肺部感染的一部分细胞破坏了粘膜，来致人死亡，要比病毒引发细胞因子风暴更早一些、更快一些？迄今为止还没有更加详细的临床医学观测大数据，更没有可以依据的结果。所以，我们放弃这方面的信息，另辟蹊径。我认为，如果你也有你喜歡的藥物，你可以同時使用它們，与我们的富勒烯聚磷酸二钠相结合。我們還將試圖展示這種病毒爆炸（病毒引发人体免疫系统的细胞因子风暴），或者病毒膜融合是如何在沒有膜的情況下發生的？我們還將討論“病毒进入人体以后”的復制平臺，以及如何為它們解壓？這是在人体被感染之後，临床医学知道如何處理病患者被感染的事實。有沒有什麼方法，可以阻止病毒將人体用作復制源，以及临床医学可以提出的任何類型的消除这种“复制平台”的答案呢？现在全世界都没有恰到好处的疫苗，临床医学只能是使用一些效果没把握的药品。這些抗病毒藥物，必須能夠解決“病毒”造成的人体“受害”所有這些問題，这是现实当中根本就不可能一揽子解决的千头万绪老大难问题。从2003年SARS病毒引发非典型性肺炎开始，我们花了很多年才把這些東西放在一起，来综合性的考虑。我们在探索发现了多年的病毒學研究情况下，和我们進入這個領域的思维定式，都不是作為生物學家、临床医学专家，而是作為病理学专家和纳米材料科學家，着眼点在于病毒处于纳米水平，一定要把病毒当成一种纳米材料存在，要站在納米生物復合材料專業的坐标系上剖析病毒。所以，我们不會把病毒看成是一種智能納米顆粒，不像现在的临床医学专家那样把病毒看的十分诡异，好像是病毒已经神秘莫测的具有了智能化水平，让现代医学捉摸不透。
To this end, I am going to talk about the electrostatic virus structure. This is besides those properties of sodium phosphates which enable them to deliver antibodies as well as other antivirals, and disintegrate viruses and bacterias. This is neither a one-stop shop mentality, nor a path dependence that raises a battle between drugs and viruses or focuses on boosting immune system with drugs.
We learnt from the dissection of coronavirus cadavers that the absence of cytokine storm in human immune system indicates injuries to respiratory mucosa. The debate on whether the virus causes deaths through patients’ complications or the destruction of mucosa by the cells in infected lungs prior to viruses inducing cytokine storm remains inconclusive. So far we have no big data from clinical trials, not to mention reliable results to base on. That is why we give up on this aspect and begin exploring other alternatives.
I believe that if you have some drug that you like that works too, you can use them as well in conjunction with our fullerene disodium phosphate. We have tried to demonstrate this viral explosion (cytokine storm induced by virus), or viral membrane fusion can happen without a membrane. We also discussed about replication platforms and how to unzip for them. That is after a patient has been infected. Clinical medicine will know what to do about the fact that a patient has been infected. Is there any way to stop it from using humans as a replication source, and any kind of an answer in regards to eliminating these replication platforms one can come up with?
The world has yet to propose a viable vaccine, while clinical medicine can only use drugs with no guaranteed effects. These antivirals must be able to address all the injuries caused by the virus, however it is a complicated issue that is, realistically speaking, difficult to address in one go. It has taken us years since SARS in 2003 to put everything together for a comprehensive approach. With years of virology research and we come into the field not as a biologist or clinical medical professional but as a pathologist with a specialty in nano bio-composites, focusing on the virus at a nano-scale, treating viruses as a nano-material, analyzing them on the axis of nano bio-composite. We are not going to be looking at the virus as anything more than a smart nanoparticle, instead of something mysterious and bizarre like many clinical medical specialists do, as if these viruses have miraculously gained intelligence that is beyond the comprehension of contemporary medicine.
2、我告诉现代医学专家，當你看到像冠狀病毒這樣的物质粒子時，我把它看作是一個物理化学结构的存在，或者说物体、化学物质。我认为病毒的基因与物理化学结构更加贴近，在病毒还没有与人体细胞发生“生命力融合”的情况下，一下子击破病毒的结构，毁坏病毒的基因，是最容易的战胜之道。
I told these modern medical specialists that when I look at a virus particle like the Coronavirus, I see as a physicist an existence of a physical-chemical structure, or an object, a chemical substance. I think the viral genes are closer to physical-chemical structure. Breaking the viral structure and destroy their genes in one swift blow before the virus fuses with human cells is the easiest path to victory.
要做到这一点，首先必须看清楚病毒上面有很多尖峰，或者说“触突”，这是病毒与人类细胞发生关系的第一部位。这种尖峰末端有負電荷，有點像日冕。好比静电实验，你把手放在一個玻璃球裡面，有一點高電壓和一些低壓下的真空氬氣。放電效應告訴你，當你穿過球時，閃電跟隨你的手指，這就是我想讓你想到的這個冠狀病毒。因為冠狀病毒，也是静电结构的物理化学“存在体”，原则上来说还不是“生物”，没有“生命力”，只有物理化学属性。此时此刻，难道说你不认为病毒是一种静电载体吗？這很重要，因為我們人类也是靜電生物，這是生物细胞的物理化学观点，就像遗传基因双螺旋结构那样，物理化学可以解读遗传基因的最基本问题。為了讓我們的富勒烯聚磷酸二钠團結在一起，我們得到了病毒必須破壞的脂肪膜。众所周知，病毒必須以某種方式粘在人类的體內，穿透人体細胞膜外磷脂酰膽鹼之間的電荷吸引，在細胞膜內磷脂酰絲氨酸进行寄生，复制，改变人体细胞，以及组织。
To do that, we must first observe the spikes, or synapses, on the virus, where the virus first make contact with human cells. At the end of these spikes are negatively charged, like a corona. Like in a static electricity experiment, when you place your hand on a glass sphere with a little bit of high voltage inside and some evacuated argon gas at low pressure. The discharge effect shows you where the lightning follows your fingers when you are going across the ball, and that is how I want you to think of this creature.
It is important because these viruses are electrostatic creatures, in principle they are not living organisms, possessing no life and only physical-chemical properties. Won’t you regard the virus as an electrostatic vessel? This is important, because we are too electrostatic creatures. This is a physical chemical perspective on biological cells, much like double-stranded DNA molecules. Physical chemistry can decipher the most fundamental question to human genetics. For our fullerene disodium phosphate to bind together, we must got this fatty membrane that the virus must breach. As everyone knows, the virus must stick inside us somehow, penetrate the charge attraction that we have between our phosphatidylcholine on the outside of our cell membranes, where inside we have phosphatidylserine, in order to feed on us, replicate, change human cells and issues.
在人体细胞內部，我們有一個負信號的磷基，和一個正信號的氮基。即使在细胞外面，我們也有同樣的部分：人体细胞有一個氨基酸，它有一個從氧氣中提取出來的負電荷，它伸進細胞生理間隙，然後细胞又得到了這個正電荷和磷的負電荷。所以，有一個共同點就是我們人体细胞与病毒同样的有氮和磷。從化學的角度來說，這可能和我們將要得到的一樣深，但我想提醒临床医学家的是，這兩個都是含磷的分子。病毒把我們人体的细胞當作食物，當作寄生的复制平台。病毒會尋找磷元素，所有關於這些被水溶性氨基酸覆蓋的穗狀糖蛋白的東西，就是尋找並結合兩個磷電荷。搞清楚这一点，临床医学专家必須了解spike糖蛋白。如果你這樣做，意味著你已經睜開眼睛進入這個另类的世界，因為病毒像饿狼一樣看著人体细胞。急不可待的病毒，我們的诺贝尔奖成果富勒烯聚磷酸二钠會盡量滿足病毒的需要，就像獵人給動物設陷阱一樣，你必須用它想要的東西，來逗它，引狼入陷阱。現在看看病毒是怎麼進入我們人类的體內呢？如果你知道磷脂酰膽鹼分子在空間中的正負電荷之間的偏移量只有幾納米，你就會明白細胞膜是如何增強的。它們是膜，不是牆，但你可以把它們看作是一種結構，設計用來防止外面的東西進來。任何試圖破壞我們人体细胞的東西，都需要以某種方式剝離正負静电，抵消这种保护层的膜。這些细胞膜，就像磚塊一樣，被病毒抵消了一點點，病毒的“触突”就可以乘机进入人体细胞。如果你看一堵磚牆，你會看到每一塊磚頭，都位於它下麵的一個接縫的頂部。病毒以同樣的方式，抵消人体细胞這些正負電荷，使得這些來自磷脂酰膽鹼的電荷，被病毒剋服，病毒才能感染我們人体的细胞。為了找到我們的人体细胞这种缝隙，病毒與它識別為人類受體的ACE2蛋白結合。
On the inside, we have a phosphorus group which has a negative sign, and a nitrogen group which has a positive sign. Even on the outside we've got these same moieties: we've got an amino acid which has a minus from the oxygen that sticks out into the cells physiological intercellular spaces and then you've got this positive amine and this negative charge again from the phosphorus. Now in terms of chemistry that is maybe as deep as we are going to get, but what I want to call attention to from the clinical medical specialists is the fact that these are both phosphorus containing molecules. To understand this, these specialists must first learn about spike glycoproteins. Do that, and you will open your eyes to an alternate world, because the virus is looking at us like food. Our Nobel winning fullerene disodium phosphate will satisfy the needs of desperate viruses like hunters placing traps for their preys. You have to tease it with something that it wants and lure it into our trap. Now let us take a look on how it get inside of us. If you understand that the phosphatidylcholine molecules are offset just a little bit plus and minus, to the minus and plus charges in space by just a few nanometers, you will understand how it is that the cell membranes reinforce. They are membranes, not walls, but you can think of them as a structure that's designed to keep what's outside from coming in. Anything that tries to breach us needs to somehow peel apart the minus-and-plus, plus-and-minus offsets. The charges are offset by just a little bit just like bricks. If you look at a brick wall, you will see that each brick is on top of a seam from the one below it. Offsetting these plus and minus in the same way, these charges from the phosphatidylcholine need to be overcome by the virus to infect us. To find us, it binds with the ACE2 protein which it recognizes as the human receptor.
在这里，有一個概念，我们稱之為靜電毒力。我们發展了一種靜電毒力理論，來描述我之前所討論的内容。我註意到這一點並提出這個理論的原因是，如果你沒有一個好的理論，你就不知道下一步該怎麼做。此即，理論就是一切科学技术探索发现的指路明灯。然而這只是冰山的一角：它可以讓你提出問題並建立模型，然後你可以在一些有意義的東西上測試你的模型。也有可能让你误入歧途，许许多多的科学家都是这样的被引导跑偏了。在這種情況下，對我们來說有意義的，是觀察到這些糖蛋白中氯的存在。那個綠點是我對氯的代表。我在公開的spike糖蛋白數據庫中註意到，作為X射線晶體學的材料科學研究专家团队，我们知道所有冠狀病毒的中心都有氯。為什麼這很重要呢？因为全世界的科学家大多數人承認這並不重要，这种氯没有构成病毒的战斗力。
There is a concept of what we call electrostatic virulence. We developed a theory of electrostatic virulence to describe what qw previously discussed. The reason I noticed this and came up with this theory is that if you do not have a good theory you do not really know where to go next. Hence, a theory is our guide to all technological discoveries. That is the tip of the iceberg: it lets you ask questions and build models, and then you can test your models on something that makes sense. In this case what made sense to me is the observation of the presence of chlorine in each of these spiked glycoproteins. That little green dot there is my representation for chlorine. I noticed in the publicly available databases for spike glycoproteins, looking as a material scientist at the X Ray crystallography of these proteins, that all the coronaviruses have chlorine right down the center of them. Now why is this important? Most people admit that it is not important, as chlorine does not constitute the capabilities of the virus.
正是如此，其他的科学家只是記錄了氯原子的位置然後繼續前進，他們對病毒中心部分的內容不感興趣，他們對病毒外部的形狀很感興趣，因為這是临床医学傳統上結合抗體的方式。這也是唯一的固體和可溶性物質，可以攜帶藥物進入體內。那麼，為什麼有人會關心病毒里有什麼東西呢，而科学实验当中许多科学家都是無論如何都無法得到呢？這就是我们與临床医学专家、与生物學家們的不同之處。临床医学专家、生物学家都不像納米技術專家那樣思考，也不像物理學家那樣思考。物理學家會尋找這樣的東西：哦，天哪！負電荷是從哪裡來的？而临床医学专家感觉到正负电荷距离肺部感染太遥远了，你们这样的隔山打牛，有意思嗎？這就是八仙过海的全世界专家教授围绕着新冠肺炎病毒COVID-19或者说SARS-CoV-2如何寻找解决方案，才发现我们的现代医学竟然没有相应的理论。当我们百家争鸣的需要尽快建立一個理論时，偏偏是百花齐放的各路专家教授彼此的立足点不一样。实践检验真理，我们体会到了曲径通幽处，禅房花木深，原因是我们找到了一条路，这是现有的其他科学家团队都没有看到的，我希望在中国首先开花结果，普惠全人类，也是解救全人类，功德无量，善莫大焉，让我们在这里得道成仙。
For that reason, other scientists just recorded the locations of the chlorine atoms and they move on. They are not interested in what is in the hydrophobic center section. They are interested in what the shape of the outside of that virus is because that is how you traditionally bond antibodies. That is the only thing that is solid and soluble that can carry drugs into the body. So why would anybody care about what's inside the virus that you can't get to anyway? And this is where I beg to differ with clinical medical specialists and biologists. They are not thinking like nanotechnologists and they are not thinking like physicists. A physicist will look for things like: “Oh Gee! Where is all that minus charge coming from?” The clinical medical specialists feel that these positive and negative charges are too distant from respiratory infections, and that any effort spent on it is just beating around the bush. This is when all the world specialists and scientists are gathering around Covid-19 or SARS-CoV-2 for a solution, only to realize that our modern medicine offer no corresponding theories. When we are so close to establishing a theory, and yet all the professionals do not share a common ground. By engaging and examining the truth, we have discovered a path that other teams of scientists fail to notice. I hope the achievement would bloom in China and then to the whole world, saving countless lives under the threat of the pandemic.
3、关于围剿病毒的方案，或者理论与实践，任何一个科学家团队，都可以根據觀察結果，来構建它，並且前提条件是數據让其他人都可用来验证。对此，我要说的是，土耳其冠狀病毒，还有中國“非洲猪瘟”所有的死豬，或者鸡瘟禽流感，都死於各自感染的病毒，這一些病毒已經存在了幾千年和幾十萬年了。它昨天沒有進化，现在也比较少发现新的变异。然而，這一切都有一個共同點：一種滲透任何動物細胞膜的方法，這種方法是靜電法。這不僅僅是化學作用，而且，使這種病毒特別危險的是，棘突糖蛋白上所有氨基酸的外部形狀，都能很快地重新配置和變異，從而跳過物種界限。这是人类感染动物身上的新冠肺炎病毒COVID-19或者说SARS-CoV-2最大的路径，我们可以預見，有一天其他的病毒也可能會在人類身上找到其他受體，使這種病毒比現在更具傳染性。這是我們需要害怕的，因為它是在人類中出乎意料的时候发生了夺命大战，让我们现代医学的套路一下子就失灵了。我們目前從武漢的医疗专家教授发表在世界学术期刊上那些報告，至少看到了有35種冠狀病毒。随后，这种武汉肺炎新型冠状病毒的变异，短短几个月，就发展到了数以千计的变异。如果你把這幾個月的時間推斷到整個人類，那麼到明年將會有成千上萬的冠狀病毒變種或分支，这是非常可想而知的推断。如果我們面对这种现实，怎么能為数以千计的新型冠状病毒開發至少千百种疫苗呢？应该说，现有的医学科技做不到，我们人类科技水平不能被病毒变异牵着鼻子走，也不能保证疫苗在很長一段時間內都是有效的。我认为，疫苗都在糖蛋白的外面，糖蛋白是變化最大的東西，真不容易依靠疫苗战胜现在日益增加的病毒变异。然而，我们绝大多数科学家都同意我的最基本假設：即使是在冠狀病毒的三千多個变异分支之間，也根本不會改變的東西是靜電基序，它是負電荷，兩個鍵合的內部氯離子之間的距離完全相同。這就是我所說的靜電毒力，我們需要瞭解它是如何運作的？
In regards on how to eliminate the virus, any scientific teams can build any theories or practices based on observations, with the premise that the data is available to be validated by others. What I am trying to say is that Turkey coronaviruses, all those dead pigs in China dying from a Coronavirus that infests pigs, or avian influenzas, all died from respective viruses they are infected by. Coronavirus has been around for thousands and hundreds of thousands of years. It did not evolve yesterday. Yet it all has this one thing in common: a method of penetration of any animal cell membrane, and that method is electrostatic. It is not just chemical, and what makes this virus particularly dangerous is that the outside shapes of all the amino acids on the spike glycoproteins can reconfigure and mutate very rapidly, so that it does jump species boundaries. This is how Covid-19 is able to jump from animals to humans. I can foresee that it can and may find one day perhaps some other receptor in the human being to make this virus even more infective than it presently is. That is what we need to be afraid of, now that it is in human populations. We presently have a report from professor doctor Li in Wuhan that there are 35 coronaviruses. 35 means we started out with maybe one. If you extrapolate that over the period of months to the entire human population then it is very conceivable that by next year will have thousands of coronavirus variants or clades. If we do, can you develop a vaccine for some of them? There is no guarantee that it would be a vaccine for any of the rest of them, or that it is even going to be any good for very long. The vaccines all go on the outside of that glycoprotein which is the thing that changes the most. Yet I hypothesize that the thing that changes not at all, in fact not at all between even clades of coronaviruses, is the electrostatic motif, which is the minus charges spaced with the exact same distance between either of the bonded internal chlorine ions. That is what I call electrostatic virulence. We need to understand how that operates.
这时候碰巧我們知道，這種病毒在二價陽離子的存在下，變得更具毒性，當然鈣是使它更具毒性的物質。這已經在现代医学的数以百万计临床医学检测报告当中，被确认了，也是病毒研究確定了的结论。這不是我们想出來的數據，而是人們多年來已經知道的基本常识。所以我問自己：為什麼這很重要？我意識到這很重要的原因，是我把病毒当成物理化学存在，绝不是人体细胞组织那种存在，没有神经系统。如果外部二價陽離子與兩個內部氯負電荷結合，即使在一定距離內，仍然會得到一些氫鍵效應，这是物理化学的基本规律性。間距看起來就像我們的卵磷脂，就像我們細胞外帶電端的那部分。這是允許膜融合發生的機制，这种間隔電荷假裝是我們捕捉病毒的抓手，原因是病毒尋找我們人体细胞的磷，也就是尋找這個电荷化合价的負加減模式，病毒試圖把自己變成一個負加減的東西，這有點像偽裝成我們人体细胞自己的脂質。
It happens to be that we know that this virus becomes more virulent in the presence of a divalent cation and of course calcium is the thing that makes it very much more virulent. This has been determined in vitro already. This is not data that we come up with, it is what people already knew for years. So I asked myself the question: why is this important? And I realized the reason it is important is because I see the virus in terms of physical chemistry, not in terms of human cells and tissues, without nervous system. If the external divalent cation bonds to the two internal chlorine minus charges, even at a distance, you still get some hydrogen bonding effects going on. The spacing looks almost like our phosphatidylcholine, like that part of us that is on the charged ends at the outside of our cells. This is the mechanism that allows membrane Fusion to happen. The spaced charges pretend to be like ours. It looks for our phosphorus, and it looks for this minus plus minus pattern, and it tries to make itself into something that's also a minus plus minus, you see? It is kind of like masquerading as some of our own lipids.
我们的诱导病毒、灭杀病毒的设计目標，是識別這些冠狀病毒究竟是什麼状态在人体细胞附近伺机而动？並找出一些方法來清除它們，我们的科学实验与临床医学观测相一致，发现此时此刻的病毒是穩定的，因為這些病毒就是帶負電荷的蛋白質，和這個spike糖蛋白內疏水區的氨基之間，已经發生了靜電鍵。这种静电键，在不断的向人体细胞渗透，如果我們通過引起電荷不平衡來取代這種結合或將其取出，我們就可以開始解開這些蛋白質，即病毒。但當我說拆開病毒的包裝時，我指的是一種膜融合類型的事件，物理化学规律上沒有脂質膜可以融合進去，所以我們可以解開這些尖峰糖蛋白，基本上給冠狀病毒一個剪發——理发店那种修剪。所以這需要一點物理化学知識，让你看到這些病毒氯原子的電荷集中在那個上下起伏的綠色波瓣上，這個波瓣的兩端都與水分子氫鍵在一起。這就是在病毒這個2.1納米的走廊里，將糖蛋白結合在一起的東西。為什麼這麼重要？當你得到氫鍵時，就會發生電荷局部化。電荷離域，發生在沒有直接鍵的地方。這些其他的電子裂片，有所謂的態密度，或整個赤道區域的電荷分佈。這是一幅漫畫，展示了病毒在人体细胞组织上渗透的事件，是如何發生的过程？
Our objective is to recognize what these coronaviruses are and figure out some way to remove them. Our scientific experiment is in agreement with clinical observations that it is stable because of the electrostatic bonding that is going on between these minus charged proteins and the amino groups in the hydrophobic regions inside this spike glycoprotein. If we replace that bonding or take it out by causing a charge imbalance, we could initiate the unwrapping of these proteins. But when I say unwrapping, I mean a membrane fusion type event without physically having a lipid membrane to fuse into, so we can unravel these spike glycoproteins and basically give the coronavirus a haircut. So now this takes a little bit of physics. I must bring a little bit of physics into this. You will see that these chlorine atoms are charge localized in that green lobe that goes up and down which is hydrogen bonded to a water molecule at either end. That is what is being held inside this 2.1 nanometer corridor that holds the glycoprotein together. Why is that important? Charge localization happens when you get hydrogen bonding. Charge delocalization happens where there is no direct bond anywhere. These other electron lobes have what is called a density of states or distribution of charge throughout the Equatorial area. This is a cartoon that shows how virus infiltrate human cells.
这方面的全世界公开医学科技成果可以查看数以百计的论文和实验，至少已經在2019年建模，當進行膜融合時，中心的三種糖蛋白將在確認中轉移。當它成為我們人体細胞膜的一部分時，病毒就像紗線一樣溶解並縫入我們人体细胞组织，或者说进入我们體內的肺部，就像在線圈之間來回纏繞的鉤編或編織一樣。这种情况下，只有我們人体细胞是被縫合的東西，我们的肺部事实上就会被不断复制的病毒建立包围圈。為此，要想着瓦解病毒，我们的切入点就是把病毒內部疏水區，和病毒外部的親水區必須改變位置，並且當病毒的触角尖峰在正確的靜電場中時，它們會通過在氯周圍進行棘輪操作，來改變其確認性。換句話說，在將ACE2蛋白接受到該一般區域後，將刺突插入我們人体细胞组织的細胞脂質中，完成病毒操纵人体细胞的寄生程序。
There are hundreds of theses and experiments all over the world on what we have discovered, and it has been modeled as early as 2019 that the central three glycoproteins will shift in confirmation as it undergoes membrane Fusion. When it become part of our cell membranes, it does so by dissolving and stitching into us like a yarn, as if doing crocheting or knitting where a thread gets wound back and forth between loops. Only we are what is being stitched. For this to unstitch, the inner hydrophobic region and the outer hydrophilic region must change places, and they do so by ratcheting around chlorine when the spike is in the correct electrostatic field to change its confirmation. In other words when the spike is inserted into our cell lipids after the ACE2 protein is being accepted into this general region, completing its manipulation of human cells.
4、我们灭杀病毒要做的是，首先激活此功能，欲擒故纵，以便让科学家们都可以看到這種情況的行之有效，属于关键时刻抓住机遇单刀直入，一招制敌。这一切都是已發布的病毒实验數據，這不是我们凭空想象出来的事情。我们所做的有用功，是在病毒中心添加了氯的存在，而這對我们來說是全部相应的学术期刊和其他出版物中所缺少的，是被忽略的最关键要害之处。
What we want to do, in order to kill the virus, is to make this activation, playing hard to get, giving the virus a one swift blow at the key moment, and show scientists how and why this is an effective approach. It is published data, of course. It is not something we came up with. What we have done is we have added in the center, the presence of chlorine, and that to us is what was missing in the publication. It is ignored. For some reason they modeled everything else and they ignored the presence of the chlorine.
由於某種原因，全世界的科学家们為病毒建立所有模型，基本上都可以局部的验证。这种建模，关键是忽略了氯的存在。現在，我们了解到这种“氯”信息是如何工作的？甚至我们都不需要创新，因為我们是基於他們的成熟理論，进行大方向的转变。现在的病毒研究，一致性的发现，是在病毒中心，看到了三個尖峰糖蛋白？這三種蛋白質打開和關閉，也就是當它們耦合到我們人体细胞组织內時，中間呈三角形的迴旋鏢，就構成了我們现有的一切疫苗都無法到達的區域。世界上沒有一種疫苗，可以滲透到病毒的疏水區域。這是為什麼呢？人体细胞组织，和病毒的结构，注定了不通過血液運輸疏水性藥物。無論我們是從白蛋白中獲取它，還是通過進食和消化系統獲取它，所有血液和血漿藥物都必須是水溶性的，才能在人体细胞组织的任何地方，去做任何事情。疫苗所做的一切都要求其水溶性，才可分佈並靶向組織。如果無法將其放入水中，則無法將其運送到需要放置的地方。在緩解冠狀病毒方面，临床医学已经部分成功的所有抗病毒藥物中，只有一種或兩種、不超过三种已經成功，因為它們在分子上具有疏水區域，但它們不是很大。我認為製作這些東西的人，甚至都不了解它為什麼起作用。我在這裡，是基於對這一點的了解，而設計的富勒烯聚磷酸二钠分子。這是個好像足球的东西，一個面是碳面富勒烯。這意味著它是親脂的，它會粘在油上；这种富勒烯聚磷酸二钠另一張脸面上，電荷高且帶負電荷。現在為什麼要選擇負電荷呢？這是因為病毒的尖峰糖蛋白的疏水區域內部，帶有高价位的正電荷，而其中唯一帶負電荷的是將其結合在一起的氯離子。
For some reason the scientists around the world modeled everything else and they ignored the presence of the chlorine. Now we understand how this works in a way that even previous researches did not understand, because I built on their theory. The current virus studies have found that there are three spike glycoproteins in the center the confirmation. Those three proteins opening and closing, that is when it couples into us. The triangular shaped boomerang in the center that constitutes the region that none of our vaccines can reach. There is not a vaccine in the world that is going to penetrate a hydrophobic region. Why is that? We do not transport hydrophobic drugs through our blood. Whether we get it in albumin, whether we get it through eating something and going through our digestive system, all blood and plasma drugs must be water soluble to get anywhere to do anything. Everything that a vaccine does requires it to be water soluble, to be distributed and target tissues. If you cannot put it into water, you cannot get it to where it needs to go. Of all the antiviral drugs that have been partially successful at mitigating coronavirus, there has only been one or two of those that have been successful because they have hydrophobic regions on the molecule, but they are not very large. I do not think that the people that that make this stuff even understand why it works. What I have here is a design of a molecule based on the understanding up to this point. One face of this ball is a carbon faced fullerene. That means it is lipophilic; it will stick to oil. The other face is highly charged and has negative charges. Now why did I pick negative charge? It is because the inside of the hydrophobic region of the spike glycoprotein is highly positively charged, and the only thing in it that is negatively charged are the chlorine ions that are holding it together.
此时此刻的最重要切入点，就是電荷各向異性。你知道什麼是電荷各向異性嗎？這意味著一個區域中有電荷，而另一區域中沒有電荷。病毒需要電荷對稱才能運行，並保持穩定。任何破壞病毒結構中電荷對稱性的東西（將其拆散），都是灭杀病毒的核心打击力，這就是我的理论与实践指导思想。 富勒烯C60分子的設計,不僅可以消除電荷，還可以模擬這種病毒的成功策略是什麼?即Corona,這是一個電暈，周圍充滿負電荷。这种实验和临床医学观测，都會發現帶有負電荷的球,看起來像這些冠狀病毒本身的縮影。我們已經巧妙地製作了一種冠狀病毒的微型“道具”，其大小不到真正的冠狀病毒的1500倍。我們將在這些尖峰結束時使用磷，就像使用它的糖蛋白尋找磷一樣。因此，我們將為它提供所需的東西，並且看起來也一樣，因為它的靜電圖案已在自然界證明了是成功的。我們不會重新發明輪子去碾压病毒触角，我們採取一個成功的靜電母体，我們復制它。我們的靜電圖谱，是在更小的範圍內復制的。現在，當這個球把自己引入疏水區域時，它的碳面上沒有官能團，它會被吸引到那個區域，從而踢出那個小綠點；那就是氯，它會說再見——病毒因此成为无心菜，丧失了害人的结构。為什麼會這樣呢？這是因為病毒得到的東西，就是聚磷酸二钠，有很多負電荷，可以包围病毒的氯元素。使得病毒的核心层那种核酸，會被吸引的失去自我。但請註意，這個富勒烯球的一個面非常親水，所以它會粘在這些病毒蛋白質尖峰的外面。在那裡，我们已經區分了含有氨基酸的蛋白質，它們是病毒疏水的（如灰色），和親水的（白色）。棒子末端的白色小球是親水性氨基酸基，這些群體一直在變異，造成了新冠肺炎病毒COVID-19或者说SARS-CoV-2的变化无穷，從一個病毒分支和一個病毒株轉變到另一個病毒株。这种情况下，你會註意到棍子末端的灰色球是病毒疏水性氨基酸，它們幾乎從不改變；它們確實有一點改變，但它們是高度保守的。這對于任何生物學家來說，都是個危險信號。它們為什麼被保存？為什麼他們總是這樣？那是因為，病毒那裡什麼也進不去。他們從不改變內心，因為沒有必要改變，當什麼都沒有進入，病毒才永远的都是病毒。但現在我们有了一個針對那個區域的富勒烯聚磷酸二钠分子，它是一種納米顆粒，是一種設計好的分子。在我们把它概念化之前，它從未存在於自然界中，这种富勒烯聚磷酸二钠纯粹的就是人类的高科技产物。這個分子不存在于大自然，迄今为止沒有其他人合成它，沒有歷史記錄公布，只有我们的实验室做出来了，并且已经通过了中间实验，进入了工厂的生产。世界上沒有任何關於這個分子的理论文章，我们可以把这种富勒烯聚磷酸二钠用到任何地方，例如中国大陆武汉市、哈尔滨之类的新冠肺炎重灾区。所以，我們已經面臨著一個巨大的無法逾越的障礙，这就是从中国到美国的治病救人通道，或者说一带一路被川普总统封锁了通道，我該怎麼想呢？像這樣的“特效药”被用在每个病患者的身体上，是否铸就“中国拯救全人类的”辉煌？我得說它是用無毒的東西製成的，是老天爷给予人类的救命稻草。翻看全人类的科技文献，30多年來，膦酸鹽一直被證明是無毒的，我们選擇的這個基團不是1996年诺贝尔奖成果的那种富勒烯了，而是磷酸鹽作为基础平台的衍生品。這也有30年的歷史了，它被用在釀酒葡萄上，以防止真菌在葡萄上生長。如果你在生命中的某個時刻喝過酒，那麼你的酒中可能含有磷酸鹽。這種結構的組合，使這種靜電針置換器不是由有毒材料製成的。我想我們有機會做一些非常創新的事情，用這種結構來代替氯。
What really matters right now is charge anisotropy. Do you know what charge anisotropy is? It means that there's charge in one area where there is not charge in another. Virus requires charge symmetry to operate and to stay stable. Anything that disrupts that charge symmetry in the structure of the virus (takes it apart), and that is my hypothesis. The (fullerene) molecule is designed to not just take apart the charges, but to emulate what it is that the success strategy of this virus has been, which is their Corona. it is a Corona that has negative charges all around it. If you will notice that ball with the negative charges, looks like a miniature of these coronavirus itself. We have made intelligently a miniature coronavirus of a coronavirus, that is less than one 500 the size of the real coronavirus. We are going to use phosphorus at the end of those spikes much in the same way that it uses its glycoproteins to look for phosphorus. So, we are going to feed it what it wants to have, and we are going to look just like it does, because its electrostatic motif is demonstrated in nature to be successful. We do not reinvent the wheel. We take a successful electrostatic motif and we duplicate it. Our electrostatic motif is duplicated on a much smaller scale. Now when this ball introduces itself into the hydrophobic region, it's the carbon face that has no functional groups on it which is going to be attracted into that region that's going to kick out that little green dot; that's the chlorine, it goes bye-bye. And why does it do so? It is because you have got something that has a lot more negative charge on it then chlorine does. It is going to be attracted. But notice one face of this ball is very hydrophilic, so it is going to get stuck to the outside of the spike of those proteins. There I have differentiated the proteins that have amino acids on them which are hydrophobic (as grey) from those that are hydrophilic (and white). Those little white balls at the end of the sticks are hydrophilic amino acid groups. Those groups mutate all the time. They change from one viral clade and one virus strain to another. You will notice the Gray balls at the end of the sticks are hydrophobic amino acids. They almost never change; they do change a little bit, but they are highly conserved. That should be a red flag to any biologist. Why are they conserved? Why are they always like that? Well that is because nothing ever gets in there. They never change inside because there is no need to change when nothing ever gets in there. But I have got a molecule now that is targeted toward that region. It is a nanoparticle. It is a designed molecule. It never existed in nature prior to me conceptualizing it. This molecule did not exist. Nobody synthesized it, there is no history on it. There is nothing in the world about this molecule that ever was written about anywhere that I can cite.
我们可以把这种富勒烯聚磷酸二钠用到任何地方，例如中国大陆武汉市、哈尔滨之类的新冠肺炎重灾区。所以，我們已經面臨著一個巨大的無法逾越的障礙，这就是从中国到美国的治病救人通道，或者说一带一路被川普总统封锁了通道，我該怎麼想呢？像這樣的“特效药”被用在每个病患者的身体上，是否铸就“中国拯救全人类的”辉煌？我得說它是用無毒的東西製成的，是老天爷给予人类的救命稻草。翻看全人类的科技文献，30多年來，膦酸鹽一直被證明是無毒的，我们選擇的這個基團不是1996年诺贝尔奖成果的那种富勒烯了，而是磷酸鹽作为基础平台的衍生品。這也有30年的歷史了，它被用在釀酒葡萄上，以防止真菌在葡萄上生長。如果你在生命中的某個時刻喝過酒，那麼你的酒中可能含有磷酸鹽。這種結構的組合，使這種靜電針置換器不是由有毒材料製成的。我想我們有機會做一些非常創新的事情，用這種結構來代替氯。
We can apply fullerene disodium phosphate to anywhere in the world, like Wuhan and Harbin, China, where coronavirus strike the hardest. So what we are faced with is an enormous, unbreachable barrier, and that is a life-saving passage from China to the U.S., or that the belt and road initiative has been shutdown by President Trump. What should I think? Could the glory of China saving all humankind be achieved by delivering this drug of ours to every single coronavirus patient in the world? I have to say this is made from non-toxic material, a heaven-sent elixir to Earth. Phosphonates have been proven time and again over 30 years to be nontoxic. The group that I selected to put on this is not a phosphate group it is a phosphonate group. This has 30 years of history as well. It was applied to wine grapes to stop fungus from growing on them. If you've drunk wine at some point in your life, you probably had phosphonates in that wine. The combination of this structure to make this electrostatic pin displacer is not made from toxic materials. I thought we had a chance here of doing something very innovative, just replace the chlorine using this kind of structure.
5、讓我們從空间大小的角度，來看病毒进入人体细胞组织這個問題。我們在病毒spike糖蛋白內部有一個畫廊區域，大約是2.1納米。那是一種走廊的直徑，即使我們不能從側面得到一些東西，如果有希望用ACE2受體以外的東西穿透這種棘突糖蛋白，它最好小於2.1納米。這有道理嗎？我们非常關心的是，一定要確保我们設計的任何功能組富勒烯聚磷酸二钠，都小於這個距離。事實上，根據計算，富勒烯分子本身，60個碳的C60富勒烯分子直徑為0.9納米。一旦你把功能基團放在上面，就是膦酸鹽，你就會得到大約1.2納米。這僅僅是基於化學，考慮估算鍵長。我们沒有发明创造數據，只是根據已知的物理化学和病毒研究成果。但我们有公认的屡试不爽那些數據作为基础，我们要解决的问题是有多少膦酸鹽被放在（富勒烯）球上，才是行之有效的?我现在要重中之重指出的，是這種結構可以與鈣元素結合到一起。鈣離子+2是漂浮在細胞外的物質，它使這種病毒更具毒性。回顾我在本文一直强调的靜電毒力的理論，它要求這種尖峰糖蛋白看起來很像我們人体细胞的脂質，外表面取代內錶面的靜電電荷。這就是它如何分解、打開，並導致膜融合的问题。這種富勒烯聚磷酸二钠分子，被設計用來偷取病毒触角棘突糖蛋白上的任何鈣。为此，最重要的是看到我们的聚磷酸二钠分子携带着鈣，現在與五種磷酸鹽中的兩種氫鍵結合了。但這仍然會留下另外三個負電荷基團，這些負電荷基團可以粘附在病毒spike糖蛋白的外面。所以，即使我們還沒有使病毒變性，我們也確實通過與它結合，來消除這種病毒的毒力。我們僅僅在有這種分子存在的情況下，就降低了病毒危害人体细胞组织的毒力。
Let us look at how the virus enters human cells in terms of size. We have the Gallery region inside the spike glycoprotein which is about 2.1 nanometers. That is the diameter of a kind of hallway. Even if we could not get something in from the sides, if there was a hope of penetrating this spike glycoprotein with something other than the ACE2 receptor, it had better be smaller than 2.1 nanometers. Does that make sense? I was very concerned to make sure that whatever functional group I designed was going to be less than that distance. In fact, according to calculation, the fullerene molecule itself, the C60 fullerene molecule of 60 carbons is 0.9 nanometers in diameter. Once you put functional groups on it that are phosphonates, you get about 1.2 nanometers. That is simply based on chemistry, looking at estimating bond lengths. I do not have data; it is just based on what is known. but I do have data that tells me how many of those phosphonates are put on the (fullerene) ball, and we will get into that later. I want to point out is that this structure can bind to calcium. Calcium +2, that is the stuff floating around outside cells, and it makes this virus even more virulent. If you recall the theory of electrostatic virulence, it requires this spike glycoprotein to look a lot like our lipids, right? The outside face replaces the inside face in terms of its electrostatic charges. That is how it unravels, opens, and causes membrane fusion. This (fullerene) molecule is designed to steal away any of the calcium that is on the spike glycoprotein. Do you see that the calcium has now hydrogen bonded to two of the five (phosphonates)? But that still leaves three more minus charge groups that can stick on to the outside of the spike glycoprotein. So, we have literally taken away the virulence of this virus by bonding to it even if we have not yet denatured it. We have reduced the virulence simply in the presence of having this molecule.
再看看病毒本身約為250納米的大小，我們的富勒烯聚磷酸二钠分子只有1.2納米，我們可以用這種分子來輸送水溶性不強的藥物，进入病毒而瓦解病毒。富勒烯球的一面是親油性的，這意味著我們可以传递有效的药品物質，但以前的药品都和疫苗一样的永遠無法溶解或传递到病毒内部，仅仅是把人体细胞组织作为主战场在那里厮杀，导致了人体免疫系统的细胞因子风暴，酿成了人体细胞组织的自相残杀和肺部病变，引发其他本来就是病态的人体器官快速恶化，导致了死亡和治愈率背后的“废人”后果。然而，利用我們的富勒烯聚磷酸二钠分子，如果你發現了临床医学药品组合不同的解決方案，突然間就会感觉到我们的富勒烯聚磷酸二钠是一种运载工具，幫助人們把药品用来攻击病毒的大門打開了，用它把一種治療性分子註入到有這種病理的人身上，而在沒有藥物輸送裝置之前，临床医学的药品就无法进入病毒。当然，富勒烯二磷酸鈉也是一種錶面活性劑，可以维护人体肺部的表面活性，也能把药品之类東西帶到需要的地方，打開冠狀病毒，杀死病毒——如果你有足夠的富勒烯二磷酸鈉去對付病毒穗糖蛋白。这是解决病毒在人体器官里面復制的问题金钥匙，也是導致膜融合事件的條件。膜融合的意思是：在关键時候打開了病毒的大门，让临床医学的药品进入病毒。反过来说，如果临床医学没办法打开病毒的情况下，把一瓶又一瓶抗病毒药品注入人体，那就是让人体中毒。我们的富勒烯聚磷酸二钠不断的融合病毒，瓦解病毒，迫使病毒在人体器官里面一直都没办法进入人体細胞內，你想想，病毒會發生什麼状态呢？我告诉你，这种新冠病毒RNA會溢出，但它沒有人体的細胞核可以去感染，变成了人体免疫系统细胞的美食。事實上，一旦人体免疫系统发出预警，病毒周圍就漂浮着大量的巨噬細胞，很可能只是病毒被包裹起來，然後連同人体新陈代谢的垃圾一起被排泄扔掉。這就是我们要設計“厕所革命”的诉求缘起，也是我们设计富勒烯聚磷酸二钠分子的目標。
Let us talk about size here. The virus itself is about 250 nanometers. We know that our FDSP is only 1.2 nanometers. But we can also deliver drugs that are not very water soluble with this kind of a molecule. One face of the fullerene ball is lipophilic; that means that we can deliver substances that might be effective but can never otherwise get dissolved or delivered. Using our molecule, if you found a different solution, suddenly, the door is open to help people. Use it to get a therapeutic molecule into people that have this pathology, whereas before there was no drug delivery device. I want you to think of Fullerene di-sodium phosphonates as a sort of surfactant. It is a solid surfactant that can pick up something and bring it where it needs to go. Of course, it can also open the coronavirus if you have enough of the fullerene di-sodium phosphonates on the spike glycoproteins. It is going to cause it to reproduce the conditions leading to a membrane fusion event. Membrane fusion means: it is time to open. If you open this thing up and it is not within the cell, what's going to happen to this virus? Well, that is right, the RNA is going to get spilled out, but it does not have a nucleus to infect. In fact, it has got lots of macrophages floating around, and it will probably just be enveloped and can be thrown out with the trash. That was the goal of the design objective behind our Toilet Revolution, as well as the design of our fullerene molecules.
6、現在你的人体可能被武汉肺炎新型冠状病毒感染了，我們不按照现有的临床医学套路去治疗，那么，我们該怎麼辦呢？观测那些纏繞在人体器官細胞內部的病毒尖峰糖蛋白，就像一個女人拿著一根編織針把一根線穿過那些環，或者说进入人体细胞的病毒有點就像手榴彈爆炸後的彈片，但不是金屬碎片，而是這些細絲，它們吸引自己進入人体细胞的高爾基復合體和線粒體，縫合人体细胞的線粒體。而這些狹窄的空間，是復制病毒所必需的。如果沒有這些狹窄的靜電空間，兩個細胞膜上的磷酸基團接近，這種病毒就無法復制。這些碎屑，和已經註入的細絲，再加上这些環，都是需要變性的，以防止我們人体细胞自己被拉上拉鏈，这种人体细胞的自我保护举措，恰恰就被病毒利用了。这样的拉鏈，是病毒復制時發生的负面事情。所以，要阻止病毒在人体细胞组织的復制，我們就需要解壓縮拉鏈。我们调查研究了全世界所有的这方面信息，還沒有在其他任何地方找到任何人，例如任何一个生物學家，看到他們提出了解壓的理論——解开病毒在人体细胞当中利用的拉链。当然，学术界有成百上千的關於人体细胞组织的拉鏈的科研文件，但似乎沒有人知道如何阻止人体细胞发生拉链现象。这是因為临床医学专家虽然发现了病毒在人体细胞组织当中利用拉链的问题，却让临床医学专家不像物理學家那樣思考问题。這些疏水環上有部分伸入線粒體內的胞漿，仍然是疏水的存在体，盡管它們的大部分是親水的。這些疏水區域與環的其他部分粘在一起，這些部分也是疏水的，這是縫合操作，或拉鏈扰乱人体细胞组织功能的來源。我們需要做的，就是在這里註入一個兩面分子，即Janus分子。因此，我們得到了富勒烯聚磷酸二鈉基團在球的一面具有親水性，它喜歡水，它有負電荷，它會在我們人类體內细胞上溶解，沒有問題。但富勒烯聚磷酸二钠球的另一面，是範德瓦爾斯類型的材料，不吸引水，它會像我們設計的那樣被脂肪區或疏水區吸引，但現在它不會侵入病毒的触角棘突內部結構，而是會侵入在一個環和另一個環之間的拉鏈操作中被病毒吸引的區域。就像在聖誕樹上裝飾色彩缤纷一樣，富勒烯聚磷酸二钠將裝飾這個環的頂部，把一個疏水區變成一個親水區。當長環被覆蓋或變性時，如果你认真观察就会看到，通過親水分子（面），富勒烯聚磷酸二钠將解開細胞的結構，將解壓縮已被壓縮的人体细胞區域，這就是我們實現第五個功能的方式。這個（目標）同樣重要，因為大多數疾病的病理，來自於你自己的細胞產生更多的這種病毒。如果你能阻止病毒復制平臺在人体细胞组织上形成，那就把病毒变成了孤军奋战，是任何病毒要危害人体细胞过程中，临床医学实验唯一最重要的功能——预防为主，不允许病毒衍生品出现。可是，迄今为止沒有一種抗病毒藥物，考慮到了這個理論，或者说試圖優化這種临床医学忘记了物理學的缺陷。這個“病毒空间”概念本身，作為一個理論，將徹底改變病毒學的一般基础知识，即使我们設計的分子（不是最佳的）富勒烯聚磷酸二钠，我们也將會设计制造出来一個更好的C60分子，來拯救更多的人，免於各種病毒传播类型的疾病。
Now what about the fact that you might be infected anyway? What are we going do about that? Recall those spike glycoproteins wind around inside of our cells. Remember I was talking about something that looks like a lady with a knitting needle pulling a thread through those loops? What gets put into us is kind of like shrapnel from an exploded hand grenade, but instead of metal fragments you have got these filaments, and they attract themselves into the Golgi complex, and to the mitochondria. They stitch our mitochondria closed. These narrow spaces are required to replicate the virus. Without these narrow spaces of static electric charge, having the phosphate groups of both cell membranes in proximity, this virus cannot replicate. These detritus, the filament strings that have been injected, these loops need to be denatured in order to stop ourselves from getting zippered shut. Zippering is what happens when this virus replicates. So, to stop it from replicating, we need to unzip the zippering. We yet to find anybody anywhere, any biologist, that has come up with a theory of unzippering. There are hundreds and thousands of papers on zippering, but nobody seems to know how to stop it. That is because they do not think like a physicist. Those hydrophobic loops have portions on them that stick out into the cytosol inside of our mitochondria. They are still hydrophobic even though large parts of them are hydrophilic. These hydrophobic regions stick together with other parts of the loops which are also hydrophobic, and that is the source of the stitching operation or zippering. All we need to do is have a Janus molecule, a two-faced molecule, injected into us in here. We have got it: fullerene poly di-sodium phosphonate groups on one face of that ball have hydrophilic character, it loves the water. It has got minus charges, it will dissolve inside us all with no problem, but the other side of that ball is a Van-der- Waals type material that does not attract a water. It gets attracted to fatty or hydrophobic regions just like we had designed it to do, but now instead of invading the spike internal structure, it's going to be invading the region that's attracted in the zippering operation between one loop and the other loop. It is like putting a decoration on top of a Christmas tree. It is going to decorate the top of that loop and turn a hydrophobic region into a hydrophilic region. When the long loop has been covered or denatured, if you will, by a hydrophilic molecule (face), you will unzip your cell structure. You will unzip that region that has been zippered shut, and this is how we achieve our fifth function. This (goal) is just as important because most of the disease pathology comes from your own cells producing more of this virus. If you can stop the viral replication platforms, that is the single most important function of anything (we can do). Not one antiviral drug even considers this theory or tries to optimize this kind of physics. This concept itself as a theory will revolutionize virology in general, even if my molecule that I have designed (was not optimal). People out there (can and) will understand these concepts, and (will) come up with an even better molecule to save even more people from all sorts of viral diseases.
我們在這里要切入另一个意思，認識到富勒烯作為活性氧物種猝滅劑的能力，就是能吸引負電荷，並通過用水定向雙層，將羥基自由基，和自由氧自由基聚集在一起。這就導致了所謂的自由基終止，就能够消除病患者的炎症，不出现发烧发热疾病。切记，哪裡有炎症，哪裡就有大量的自由基漂浮在周圍。临床医学在治疗武汉肺炎的过程中，清一色的都需要停止人体過多的炎症，這是治病救人的传统路线图第一要务的那个部分。
What we can do here is we can also recognize the ability of the fullerenes to act as reactive oxygen species quenchers. It attracts negative charges and (by orienting a double layer using water), it brings hydroxyl radicals and free oxygen radicals together. This causes what is called free radical termination. Remember, where there is inflammation, there is plenty of free radicals floating around. When treating Wuhan pneumonia, it is common that we need to stop too much inflammation, that is part of the problem in the traditional roadmap to curing coronavirus patient.
關於這個分子的結構和設計，我们在科学实验当中還可以看到，富勒烯聚磷酸二钠分子作為固體錶面活性劑的作用。它作為錶面活性劑，有助於人体肺部錶面活性劑的功能强化，对于新型冠状病毒的入侵起到了阻碍作用。人体的肺錶面活性物質，被從血液中取出並泵入肺部，以消除微生物的感染，包括病毒的感染。但是，人体本身的肺錶面活性物質在中老年人的器质性、退行性“走向衰弱”以后，肯定是不夠好了，身體的新陈代谢正常功能最終會被自己的肺錶面活性物質“衰败”所淹死。那就是中老年病患者肺部的膿液，阻止了他們獲得足夠的氧氣。如果临床医学能够给予人体肺部更好的錶面活性劑（人体免疫系统和新陈代谢系统協同作用），那么新冠肺炎病毒就不可能造成中老年人的批量化死亡了。因此，在設計這種富勒烯聚磷酸二钠分子的时候，我们有必要制備一種與肺錶面活性物質相容的固體錶面活性劑，必須有一個能夠吸入蒸汽的分子，快速的从人体呼吸道进入肺部。
Another thing you can look at about the structure and design of this molecule, is its role as a solid surfactant. As a surfactant it helps the function of pulmonary surfactant. Pulmonary surfactant is being taken out of the blood and pumped into the lungs to remove the microbial infection. However pulmonary surfactant is not good enough, and the body winds up drowning the patient in their own pulmonary surfactant. That is the pus that is in their lungs that is stopping them from getting enough oxygen. If we can come up with a better surfactant (synergy), then we will not have middle to old age population dying in bulks. So, it was essential in the design of this molecule to create a solid surfactant that was compatible with pulmonary surfactant.
这也是新冠肺炎病毒主要的从人类呼吸道传染进入肺部路径，针对新冠肺炎病毒的给药方式应该也是呼吸道直截了当进入人体肺部，这就是让人体吸入蒸汽状态的药品，最容易直达病灶。这也是了解我們如何將富勒烯聚磷酸二钠分子（纳米级药品）輸送，並靶向具有最嚴重病理狀態的人体器官肺部的關鍵。临床医学要求治疗工作把藥物送到人体器官最有用的地方，如果能直接將口服液輸送到靶向器官，將其濃度降低1000倍，成本就可以大幅度降低，有利于广谱性的给贫困病患者免费治疗。不过，我们的技术经济实践证明，富勒烯聚磷酸二钠有點成本太貴，我們可以把它稀釋得很稀，以至於用不到一毫升的量，來治療成千上萬的人，让治病救人變得物美价廉。我們可以把一個通常用於呼吸機的裝置，變成一個醫療救治裝置。這是一種傳遞機制，例如雾化吸入的治疗感冒发烧那种设备，也可以是電子設備的設計方案，裡面有一個芯片來接收和记录數據。因此，可以就像處方一樣跟蹤連接。我們的富勒烯聚磷酸二钠放在裡面，打开按钮开关控制器就开始雾化药品，病患者口腔吸吮这种设备的端口，使這些煙霧状态的富勒烯聚磷酸二钠和其他抗病毒药品，就沿着让人体呼吸道进入肺部。我們的临床医学实验使用甘油（溶劑），它很容易蒸發，也是一種無毒的植物原料，能很好地溶解富勒烯二磷酸鈉。 这样的话，藥物直接進入人的肺部，效果很好，例如有些人感染了冠狀病毒，仅仅是在家里面自己嘗試了這種方法，就縮短了患病時間。
The coronavirus enters our lung primarily through our respiratory tract, and the drug delivery method should do the same. That is why vapor inhalation is key to understanding how we can deliver and target this material to this organ that has the most serious pathological condition. We think that people need to deliver a medication to the site where it is going to do the most good. If you can reduce the concentration of an oral solution 1000 times by delivering it directly to the target organ, the cost would be much more affordable. I believe that even though this material is somewhat expensive, the fact is we can dilute it so much that it becomes inexpensive to treat tens of thousands of people with literally less than a milliliter each. We can take a device that has normally been used for vaping and turn it into something that is a medical therapeutic device. This is a delivery mechanism. This device has been designed with electronics in it with a download port to take the data, so the connection can be tracked like a prescription. We have a partnership with the designer of this (system), to put our material inside of it. Basically, you would suck on this end, and you would make these fumes, and it would look like vaping. That is what people call vaping, but it should not be confused with vaping, because it has got a medicinal material inside it. We are using glycerol (solvent), which can be easily vaporized. It is a nontoxic vegetable material, and it is well able to dissolve fullerene di-sodium phosphonates. Through this method, the drug directly enters the lung with desired effect. For example, if someone is infected with coronavirus, just by vapor inhalation at home would reduce the time of infection.
7、我坦诚的说，这种思路的缺陷在于，化學經常出不了實驗室，製造富勒烯聚磷酸二钠分子的化学实验在工厂化的过程中，历尽艰辛。設計它花了好幾年的時間，看到工厂类型生产线製造出來富勒烯聚磷酸二钠，並得到临床医学实验的证明，适逢武汉肺炎新型冠状病毒肆虐全世界的危险时刻，我们感觉到责任重大。我们研制的富勒烯聚磷酸二钠分子物質，溶於“水溶性”的甘油。把它再通过雾化装置，直接送到需要治療病毒性肺炎的肺部靶向器官，而不是把它稀釋到人体不需要的任何地方，例如胃部，与胃液发生化学、生物类型的反应，再进入消化系统，拐弯抹角的进入肺部，就会得不偿失。我们的从临床医学实验当中，获得的经济技术核算数据证明，雾化吸入肺部的富勒烯聚磷酸二钠分子，通常要比口服液从胃部给药，療效會提高1000倍。
Frankly speaking, the flaw along this line of thinking is that chemistry rarely leaves the lab. The chemical experiment that leads to the mass production of the fullerene molecule was difficult to say the least. It took several years for the design. Watching these molecules been produced on the production line and be validated in clinical trials in the time where coronavirus ravages the entire world, we feel an immense responsibility. Our fullerene molecules with water-soluble glycerin, placed in vaping devices, delivered directly to the organs the require treatment instead of diluted to any part of human bodies that are not needed, such as the stomach, where it reacts chemically and biologically with gastric juices, then goes into the digestive system and roundabout into the lungs. Our economic and technical accounting data obtained from clinical medical trials prove that vaporizing the fullerene disodium polyphosphate molecule inhaled into the lungs is usually 1000 times more effective than oral administration from the stomach.
我们在这里也是深入细致的调查研究了疫苗解决病毒传染问题的可操作性，对于疫苗这种“一把钥匙开一把锁”的路径依赖症，感觉到人的一生面对太多的细菌和病毒侵袭，每一个病毒打一次疫苗，究竟是要让人生一辈子打多少次疫苗啊？从此出发，任何承諾為這種病毒，一门心思接種疫苗的选择，都有最大的缺陷，那就是不知道病毒變異的速度有多快？此外，他們可能告訴善良的人们，现在全世界至少有35种病毒一对一搞疫苗，就需要35种疫苗，这一年每个人真的是要打35个疫苗吗？这些疫苗在人体内部是否会交叉反应呢？
没有临床医学研究的结果，如果我們想利用疫苗對抗埃博拉病毒、武汉肺炎病毒、寨卡病毒等等，我們需要打太多太多的疫苗针剂了，太可怕了。应该说，简单易行的解决病毒危害人类生命安全问题，根本出路的选择肯定不是疫苗。
诚然，我並不是說我们的富勒烯聚磷酸二钠分子可以治愈任何疾病，但富勒烯聚磷酸二钠确实是把武汉肺炎病毒真的瓦解了，把这样的形形色色病毒进行了由表及里的變性，就可以減緩病理學的發展，使得人体免疫系統可以接管肺部的病变而不发生细胞因子风暴，那就是在2020年拯救人类。我们的科学实验证明，自己团队的人们及其家人，恰恰是雾化吸入了富勒烯聚磷酸二钠分子，就在世界各国没有感染武汉肺炎病毒，包括在美国和意大利抗拒了武汉肺炎新型冠状病毒变异之后的类型，每天在工作室、实验室和家庭、超市、公园来回穿梭也安然无恙。
We have also studied the feasibility of vaccines to solve the problem of virus transmission in detail. In regards to this "one key, one lock” path dependency, our entire lives are met with so many bacteria and viruses, to have one vaccine for every single virus means how many vaccines we have to receive in a life time? If we continue to act like bacteria and just try to find a new way to match the shape of something that changes as quickly as this virus does, I think we have got a recipe for disaster. Anyone who promises that they have the vaccine for this virus does not understand how quickly it mutates. Also, they probably told you at least 34 lies in one statement because there are 34 other viruses that will also require a vaccine. Without the results of clinical medical studies, if we want to use vaccines against Ebola, Wuhan pneumonia virus, Zika virus, etc., we need too many too many vaccine shots, it's horrible. It should be said that the simple and easy solution to the problem of viruses endangering human life is certainly not a vaccine. We need something other than a vaccine if we want to combat this virus. I am not saying that this will cure anything, but if it does denature it, it can slow it down pathology to the point where our own immune system can take over, and that means saving humankind in 2020. Our scientific experiments proved that the people on our team and their families, precisely those who inhaled the vaporized fullerene disodium polyphosphate molecule, were not infected with Covid-19 while traveling around the world, including in the United States and Italy while exposed to the new coronavirus variants, and were safe and sound in their daily commute to and from the studio, laboratory and home, supermarkets, and parks.
我们的亲身体验当然不能代替科学实验的各种各样检测，例如使用飛行時間MALDI對我們的富勒烯聚磷酸二钠分子結構進行確認：這是一種我們確定結構的氣相色譜法。富勒烯球的分子峰，是最大的碎片之一。分子量720的碎片，富勒烯球，碳原子有60個，當碳原子質量為12的时候就質量為720。如果你在720處，對除了分子峰以外的峰，進行積分，你會發現這個結構的57%在它的排列中，大約43%在10個官能團中。為什麼這麼有趣呢？如果你看足球，你會看到它有六邊形和七邊形。七邊形是五邊碳，六邊形是6，而足球兩者都有。但很明顯，膦酸基團在6-6鍵的五邊頂點周圍，加入了五個基團。很明顯，它就像是五人一組。出於分析的考慮，我想看看能否改變我们关于富勒烯聚磷酸二钠分子的“足球状态”的反應條件。那麼，如果我們在反應中加入另一種五邊形呢？我能得到更多的磷酸鹽基團嗎？事實上，它們是否會被加入到一個五個基團中嗎？我们真的了解這種化學反應的本質嗎？我們的千百次科学实验得到了原始數據，這是正模式，這意味着富勒烯球上有一個額外的氫。這只是為了證明我們仍然有正確的分子材料和它的分子核心，即C60分子。这一点证明，我們的富勒烯聚磷酸二钠分子有三個不同的基團，這些峰被我們可以整合的膦酸鹽片段的正確排列分開。因此，如果我們把所有的峰，從1000到3000整合起來，我們應該得到一個成分，它告訴我們除了那些散裂碎片之外的所有東西的比率，以便能夠看清楚重建成分，和相對成分各是什麼？我們因此找到了一种临界分割线，这就是6%的重建成分，比率不是很高，但這足以讓我们放心了：通過控制膦酸鹽的數量，我們可以決定在球的一側加入多少膦酸鹽基團。這更多的是化學上的練習，而不是實踐上的練習，因為當你把太多的磷酸基團放在球上時，它就不再是一個雙面分子了。所以，我們的富勒烯聚磷酸二钠分子不再有一張完全沒有功能群的臉（表面），也不再有一張有愛脂臉和愛水臉的Janus型分子。但它確實證明了我們對化學物質有完全的控制權，我們可以把它送到任何制藥公司，例如中国的大型制药厂，以举国之力向全人类做贡献治病救人，按吨位的数量级进行生產。何况，富勒烯聚磷酸二钠分子制取，还不是一個復雜的反應。最接近的物質，如我之前所說，是磷酸二鈉，用於葡萄。這和我们把它粘在球上沒什麼兩樣，放在食物上是可以的。我们成千上万的科学实验证明，富勒烯聚磷酸二钠分子让人们吸氣的雾化吸入方式，是可以最容易进入肺部的。我们发现FSA對磷酸二鈉的背景，不存在任何的毒性，实验当中没有任何不良反应。
Our personal experience obviously cannot replace a variety of scientific testing, such as structural confirmation using time of flight MALDI: it is a kind type of gas chromatography where we determine our structure. The molecular peak for the fullerene ball is one of the biggest fragments that comes out of this. The fragment at 720 that is the fullerene ball, that's carbon and you have 60 of them; when you have a mass of 12 on carbon, that gives you mass 720. If you integrate the peaks except for the molecular peak at 720, you find out you get 57% of this structure in its permutations, and about 43% of 10 functional groups. Why is that interesting? If you look at the soccer ball, you will see it has both hexagons and heptagons. The heptagons are 5-sided carbons. The hexagons are 6, and a soccer ball has both. But apparently the phosphonate groups are adding in groups of five around the five-sided vertices across the 6-6 bonds. Apparently, it does so in groups of five. Being analytical, I wanted to see if I could change my reaction conditions. So what if we put another of those pentagons into the reaction? Could I get more phosphate groups, and would they in fact be added in a group of five? Do I really understand the nature of this chemistry? Here we got the raw data, this time in positive mode, which means we have got an extra hydrogen on our fullerene ball. This is just to prove that we still have the correct molecular material and its molecular core which is the C60 molecule. Yes, we have got three different groups, and those peaks are separated by just the right permutations of phosphonate pieces which we can integrate. So if we integrate all of the peaks from about 1000 up to about 3000 we should get a composition that tells us the ratio of everything that came apart from those spallation fragments, to be able to reconstruct what the composition and the relative composition was. Sure enough, we have got it! 6% was not very much but it was enough for me to be happy. I have made a very good proof of concept for this chemistry. By controlling the number of phosphonates, we can decide how much of the phosphonate groups get added on one side of the ball. This is more of an exercise in chemistry than it is an exercise in practicality, because when you put too many phosphate groups on the ball it is no longer a 2-sided molecule, is it? So, we no longer have one face that is completely free of functional groups, and we no longer have a Janus type molecule with a lipid loving face and a water loving face. But it does demonstrate that we have full control over the chemistry, and we can send this off to any pharmaceutical company, like Pfizer, and they can mass produce this by the ton if necessary. It is not a complicated reaction. the nearest closest substance as I said before is disodium phosphonate which is used on grapes. It is no different than what I stuck onto the ball. It was OK to put it on food. We think it is OK to breathe it in and that is going out on a limb, but we had to do something. We mean some human being must sit around and come up with a new idea and this is one idea. We are not guaranteeing anything, but we are saying this is a theory and it is possible that it could help a lot of people. We feel that because of the FSA background on di-sodium phosphonates that we are not worried about toxicity here.
我们一直都在討論的是，如何解開被低估的靜電病毒結構？這就是目前的理论与实践创新发展“病毒学”里程碑：到處都是氯化鈉。我們人体全是氯化鈉，氯的存在不應該令人驚訝。但在2020年武汉肺炎病毒這種泛滥成灾的情況下，我認為“病毒核酸最中心的氯”，是一個非常重要的線索，也是长期以来研究“病毒”的科学家忽视了的因素，更是抗病毒药品的临床医学实验当中被主流“医学权威理论”缺失的元素。如果不能從這些病毒中去除這些氯離子，我們就無法使它們分離，或者说不能瓦解病毒。我們打败病毒的致命性“抓手”，就是病毒能夠清除游離的鈣離子，和人体细胞组织融合，使這種病毒更能穿透我們人体細胞的原因。我們需要能夠提供富勒烯聚磷酸二钠分子的载体作用，让其他那些可能出現的候選藥物和抗體，也加入灭杀新冠肺炎病毒的战斗。我們的富勒烯聚磷酸二钠分子是很好的載體，是一種與人体肺表面活性物質協同作用的錶面活性劑，是一種固體錶面活性劑，它將與水溶性不強的藥物協同作用，以便更好地攜帶和輸送这些药物。我希望我們能使別人的發明，来更高一筹的補充我們的创新发展。
In summary, what we have talked about in this presentation is how to unpin electrostatic viral structures that have been underappreciated. That is the present inquiry: yes, there is sodium chloride everywhere. We are full of sodium chloride. Chlorine presence should not be a matter of surprise. But in this case, I think it is a very important clue and a missing element. Without being able to unpin those chlorines from these viruses, we will not be able to make them come apart. We need to be able to scavenge free calcium ions; that is what makes this virus very much more able to penetrate our cells. We need to be able to deliver other drug candidates and antibodies that might come along. We do not want to act in a vacuum. We want to work together with other people's ideas, and I think we have a great carrier. Because we have a surfactant here that works with pulmonary surfactant, and is a solid surfactant, it will work with drugs that are not very water soluble to better carry and deliver them. I hope we can enable somebody else’s invention to complement our invention.
8、我們为了避免人体细胞组织受到损伤，需要尽量的在細胞外，使這種新冠肺炎病毒變性，或者说把病毒瓦解在人体细胞的外面。我們的屡试不爽方法，就是通過將足夠的富勒烯磷酸二鈉放在spike糖蛋白的外面，使新冠肺炎病毒相信它正在經歷一個膜融合事件。我們愚弄了病毒，让病毒以為它正在入侵我們人体细胞组织。我們對待病毒，就像獵人用誘餌誘捕動物一樣——你想怎麼喂它，就怎麼喂：如果它看起來像磷，那它就是磷。這就是為什麼我們選擇了一種膦酸鹽，這樣我們就可以在人体細胞外，使病毒變性，或者说瓦解病毒的危害性能力。我们的富勒烯聚磷酸二钠不僅對病毒起作用，而且對病毒的碎片也起作用：那些在拉鏈里把富勒烯聚磷酸二钠分子縫合在一起的碎片，我們富勒烯聚磷酸二钠分子包围線粒體的病毒拉鏈，是病毒繁殖的地方。如果我們可以通過開放病毒復制平臺，來減緩這種病毒复制速度，富勒烯聚磷酸二钠分子就是在诱导病毒的同时，也诱导人体免疫系统不会过激反应，幫助人体免疫系統以一種有意義的方式，去對抗病毒，而非在人体肺部把人的细胞与病毒千篇一律格杀勿论。这时候，錶面活性劑的作用非常重要，因为它是病毒进入人体呼吸道以后，到达人体器官的第一个平台，不像人体咽喉和鼻腔的分泌物让病毒难以稳定存活。所以，病毒到达人体肺部表面上，才开始感受到了有机可乘，而人体只有改善肺錶面活性物質的功能，才可以让病毒无法进入人体细胞。肺錶面活性物質的细胞，就是首当其冲的被病毒侵害的对象。當人体受傷時，这种肺部表面活性剂就出現在人体伤口的痂下，基本上允許巨噬細胞進入並帶走微生物感染和侵入性微生物，把這些有害的因素排泄出人体。但是，很少有临床医学专家考慮過能夠利用材料科學，來增強肺錶面活性物質的操作。 这一点，恰恰是中老年人的肺部表面活性剂越来越差，被临床医学全方位忽视了，也不知道应该怎么样强化肺部表面活性剂的良好状态，因为除了富勒烯聚磷酸二钠分子以外，还没有其他的物质能够优化组合人体的肺部表面活性剂。
We need to be able to denature this virus outside of our cells. I believe we have found a way to convince the virus that it is undergoing a membrane fusion event by putting enough of this fullerene di-sodium phosphate on the outside of the spike glycoprotein. We have fooled the virus into thinking that it is doing an invasion of us. We are treating it like a Hunter does when trying to trap an animal with bait.
You feed it what you think it might like: if it looks like phosphorus, it is phosphorus, right? That's why we picked a phosphonate, so we can denature the virus outside of our cells and not only does it work on the virus, it also works on the pieces of the virus: those pieces that stitch us together in the zippering. Viral zippering of our mitochondria is where the virus multiplies. If we can slow that down by opening those viral replication platforms, we are already doing a lot to help our immune systems combat this virus in a way that makes sense. Surfactant function is very important. There is not anything else I know about where people have tried to improve pulmonary surfactant function. Pulmonary surfactant is great. It is what appears under our scabs when we get hurt. It basically allows the macrophages to come in there and take away microbial infections and invasive microbes, the bad actors. But there are very few people that have given much thought to being able to use material science to enhance the operation of pulmonary surfactant.
9、在新冠肺炎病毒的致死病例当中，解剖学发现了細胞因子风暴的更大危害性，却是一直都不明白这种“细胞因子风暴”為什麼会发生？为什么在人体免疫系统当中长期性、大面积存在呢？我们参照临床医学观察、流行病学调查、人体免疫系统研究，站在物质结构的分析立场上，就会发现細胞因子風暴是帶有許多帶正電荷的氨基的氨基酸，從尿素到任何一種偶氮化合物，導致人体炎症发生的原因。這是人体天生的免疫力路径依赖症，注定了细胞因子风暴的发生本身就是人体免疫系统最大的缺陷。如果我们的方法能讓帶負電的膦酸鹽，与帶正電的炎症分子相互結合，就是已經在做一些事情來幫助肺部錶面活性劑完成它的工作，幫助清除引起炎症的根源。這種錶面活性劑的作用是有利于人体健康的，我们成千上万次观测錶面活性劑的工作状态時，就明显的发现正負電荷之間的吸引力，在这个时候是很重要的因素。
In the death cases of coronavirus, autopsy revealed the danger of cytokine storm, but never understood what are cytokines, and why do they exist? Based on the analysis of the structure of substances with reference to clinical medical observations, epidemiological investigations, and studies of the human immune system, they are amino acids with lots of positive charged amino groups floating around, everything from urea to any kind of azo compounds. That is what causes inflammation. It is our innate immunity. If you can get a negatively charged phosphonate to bond to positively charged inflammatory molecules, you are already doing something to help that surfactant do its job, by helping to clear out the very source of what's causing the inflammation. This kind of surfactant function makes sense because the attraction between minus and plus charges are important when you start thinking about surfactants.
这样的物理化学方式方法，让我們需要把病毒看作是一个简单的機器，是聰明的納米粒子，能够利用我們人体的一部分來製造它们病毒的另一种部分。这方面可以参考计算机鼻祖馮·諾依曼，他提出了一個機器的理論，這個機器只是利用環境能量，來製造更多的自我。可以把病毒看成是馮·諾依曼自動機，这样看待病毒的方法给予我们超乎寻常的想象力：病毒是一臺機器，它有部件，它有功能，它使用電和靜電來操作這個機制。如果你知道這台機器是怎麼工作的，你就可以做一個簡單的停止操作，让病毒失去了传染能力。就像法語有一句俗话說的，我們可以進行破壞活動，或者通過扔木鞋或“木托”來拆掉工廠的木製齒輪。所以，我们提出的是“反冠狀病毒”的理念，和离开临床医学的固有观念——把病毒与人体细胞组织同等对待， 结果就是忘记了从“病毒”的基础逻辑之离子、静电、正负电荷规律性着眼看问题，不懂得“从最低端颠覆其基础规律足以消灭物种的本体”这个基本原则，使得“病毒”本来就不完整的架构明显的漏洞百出，一下子就被分化瓦解了，丧失了改变人体细胞的能力。也就是破坏了病毒的传染力，保护了人体细胞组织的常态化运行。
In this physical chemical approach, we need to start to think of these viruses as machines. They are nanoparticles that are smart. They use parts of us to make parts of them. A guy by the name of von Neumann came up with the theory of a machine that just uses ambient energy to make more of itself. You can look at a virus as being a von Neumann automaton. That is one way to look at a virus: it is a machine, it has parts, it functions, and it uses electricity and electrostatics to operate this mechanism. If you know how the machine works you can throw in a simple stop operation. Like they say in French, we can perform sabotage, or bring down the wooden gears of the factory by throwing in a wooden shoe or “sabot”, So this is a summary of the anti-coronavirus concept, a departure from the traditional view in clinical medicine—by treating viruses and human cellular tissue on an equal footing, the result is that we forget to look at the problem from the ionic, electrostatic, and positive and negative charge regularity of the basic logic of the virus, and do not understand the basic principle that "overturning the basic laws from the lowest point is sufficient to eliminate the ontology of the species", revealing the loopholes of the virus with an incomplete structure, which is immediately divided and disintegrated, losing the ability to change human cells. That is, it destroys the infectious power of the virus and protects the normal functioning of the cellular tissues of the human body.
我们的这种工艺先进性，突破了水溶性C60非用工业溶剂的困境，是目前全球唯一符合食品药品安全标准的新产品，用来作为瓦解新冠肺炎病毒COVID-19，是纳米材料的新科技和高科技成果。日本三菱集团的C60化妆品无法达到食品药品安全性标准，因为日本三菱广顺的C60含有微量PVP，这是具有致癌风险的，因此只用来做謢膚保养品。另外，我们的富勒烯聚磷酸二钠是半親油半親水的科技产品，更是世界第一也是世界唯一的纳米材料新科技，正好在2020年应急處理新冠肺炎病毒COVID-19。我们的全部富勒烯聚磷酸二钠产品，比日本三菱公司的纯油溶、或纯水溶C60基本技术超前一个时代。我们已经实现了C60用在生物及药物医学的世界领先拉动效应。形象的比喻就是，我们的聚磷酸二钠就好比富勒烯产品大世界里面的喷气式飞机，日本三菱公司的富勒烯C60还处在自行车的階段，不在一个層级上。简而言之，我们团队的富勒醇和日本三菱公司的C60差别巨大，日本三菱公司的C60为何不适合人体服用呢？科学家检测发现日本三菱公司的C60产品携带新冠病毒，不安全而我们的产品首先是食品级的，然后是药物及疫苗最好最安全的载体。我们的临床医学实验，首先对于1.呼吸道传染新冠肺炎病毒，进行中青年男子电子烟方式、妇女儿童老人的雾化器方式、鼻腔喷剂方式等至少三种以上的给药方式方法。2.根据口腔容易感染病毒的情况，采取与胃液、肠道酶友好界面的给药方式方法，确保各种各样的产品恰到好处。3.眼睛感染新冠肺炎病毒是治疗方面比较麻烦的事，我们使用低剂量的Fullerene Di-Sodium Phosphonate保养方法，也配套雾化的特定器具，快速达成治疗效果。
Our technological advancement that is the breakthrough of the predicament of water-soluble C60 without industrial solvent is the only product that complies with world’s food and drug safety standard. This innovative technological achievement based on nano-material can be used to kill Covid-19. The C60 cosmetic products by Mitsubishi does not satisfy the food and drug safety standard, because Mitsubishi's C60 contains a trace amount of PVP, which is a carcinogenic risk, so it is only used for skin care products. In addition, our fullerene disodium polyphosphate is a semi-oleophilic and semi-hydrophilic technology, the world's first and only new nanomaterial technology, just in time for the 2020 emergency treatment of the new coronavirus COVID-19. Our fullerene disodium phosphate products are one era ahead of Mitsubishi's basic technology of pure oil or water soluble C60. We have achieved the world-leading pulling effect of C60 in biomedical and pharmaceutical applications. Metaphorically speaking, our disodium polyphosphate is like a jet plane in the big world of fullerene products, Japan's Mitsubishi's fullerene C60 is still riding a bicycle, on a completely different level. In short, there is a huge difference between our team's Fullerol and Japan's Mitsubishi's C60, so why is Japan's Mitsubishi's C60 not suitable for human consumption? Scientists have found that Mitsubishi's C60 product is unsafe to carry the coronavirus, while our product is firstly food grade, then the best and safest carrier for drugs and vaccines. In our clinical trials, we first administer at least three or more drugs for respiratory infection of coronavirus, such as e-cigarette for young men, vaping device for women and children, and nasal spray for the elderly; 2, according to the susceptibility of the oral cavity to the virus, we administer drugs with friendly interface with gastric fluid and intestinal enzymes to ensure that various products are appropriate; 3, eye infection of coronavirus is a troublesome in term of treatment, who e use the low-dose Fullerene Di-Sodium Phosphonate for maintenance, coupled with specific devices for vaporization to achieve rapid treatment effect.
简而言之，效果就是硬道理。相比之下，美国索伦托公司之类的自吹自擂100%有效抗体，本身就没有直截了当的人体试验，纯粹的就是体外测评，都不敢说出来基本原理，不敢公布试验数据，不懂得“抗体”进入人体以后，与人体免疫系统、与新冠肺炎病毒之间的三角关系是什么？还有数以百计的疫苗，都是在望梅止渴画饼充饥，实质性的可操作效果，基本上都是可望不可即的乌托邦神话故事，属于新闻止痛片与精神安慰剂、麻醉剂，不值一驳。
Simply speaking, effectiveness matters. Comparatively Sorrento Therapeutics claimed to have identified an antibody against Covid-19 that is 100% effective. Without human trials, relied only in vitro testing, afraid to reveal their underlying principles and test data, ignorant of the triangle relationship among the antibody, human immune system, and Covid-19. Not to mention hundreds of vaccines that are nothing more than a wild goose chase. Without substantive operability, they are nothing more than utopian fantasies, painkillers, mental placebos, and anesthetics, unworthy of our attention.
中国光彩集团副总裁、
京中智库领袖联盟首席专家、
广顺集团首席科学家 、
国际健康科学院院士
徐群贵研究员
Vice President of Guangcai Group
Chief Expert of Jingzhong Think Tank Leadership Alliance
Chief Scientist of Guangshun Group
Academician of International Research Institute of Health Science
Researcher Xu Qungui
2020年5月14日星期四
Thursday, May 14, 2020.
六十岁的徐群贵院士参加学术会议
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Academician Xu Qungui in an academic seminar